| Preview (7:10 PM) | | Chicago Cubs (85-55) | | | Probable: Ted Lilly (13-8) | | Cincinnati Reds (62-78) | | | Probable: Bronson Arroyo (13-10) |
| | | Preview (7:10 PM) | | Philadelphia Phillies (76-64) | | | Probable: Brett Myers (8-10) | | New York Mets (79-61) | | | Probable: Mike Pelfrey (13-8) |
| | | Preview (7:30 PM) | | Washington Nationals (54-87) | | | Probable: Jason Bergmann (2-10) | | Atlanta Braves (61-80) | | | Probable: Jair Jurrjens (11-9) |
| | | Preview (8:05 PM) | | San Diego Padres (54-86) | | | Probable: Josh Geer (1-0) | | Milwaukee Brewers (80-60) | | | Probable: CC Sabathia (15-8) |
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| Preview (8:15 PM) | | Florida Marlins (71-69) | | | Probable: Ricky Nolasco (13-7) | | St. Louis Cardinals (75-65) | | | Probable: Braden Looper (12-11) |
| | | Preview (9:05 PM) | | Houston Astros (74-66) | | | Probable: Brian Moehler (10-5) | | Colorado Rockies (66-75) | | | Probable: Ubaldo Jimenez (9-12) |
| | | Preview (10:05 PM) | | Arizona Diamondbacks (71-68) | | | Probable: Dan Haren (14-7) | | Los Angeles Dodgers (70-70) | | | Probable: Derek Lowe (11-11) |
| | | Preview (10:15 PM) | | Pittsburgh Pirates (59-80) | | | Probable: Zach Duke (4-13) | | San Francisco Giants (60-79) | | | Probable: Kevin Correia (3-7) |
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